学习经历
2004，博士学位, 香港大学，(导师: 支志明院士)。
1996，硕士学位, 华东理工大学，(导师: 荣国斌教授)。
1993，学士学位, 华东理工大学。
工作经历
2018/11-现在，8455新葡萄场网站, 教授。
2012/08-2018/10，香港大学, 研究助理教授。
2012/02-2012/07，香港大学, 研究主任。
2009-2012, 香港大学, 博士后(合作导师: 支志明院士)
2007-2009, Texas A&M University, 博士后 (合作导师: Daniel Romo教授)。
2004-2007，香港大学, 助理研究员。
1996-1999，华东理工大学, 讲师,助教。
研究方向
过渡金属催化，不对称催化和合成，天然产物和药物分子合成，生物偶联和生物探针合成。
主要论文
1） Zhen Fu, Chengming Wang*, Cong-Ying Zhou*, “Alkylcarbene mediated intramolecular alkene cyclopropanation to construct aza[3.1.0] bicycles”, Org. Chem. Front. 2023, 10, 699.
2） Qianrong Li, Cong-Ying Zhou*, Chengming Wang*, “Metal-Free Generation of γ-Cyanoalkyl Radicals by N-Heterocyclic Carbene Catalysis: Assembly of 6-Cyanoalkyl Phenanthridines”, Org. Lett. 2022, 24, 9243.
3） Fujun Guan, Rong Zhou, Xiaoyu Ren, Zhen Guo*, Chengming Wang*, Cong-Ying Zhou*, “Asymmetric dearomative cyclopropanation of naphthalenes to construct polycyclic compounds”, Chem. Sci. 2022, 13, 13015.
4） Qianrong Li, Cong-Ying Zhou*, Chengming Wang*, “Divergent Construction of Heterocycles by SOMOphilic Isocyanide Insertion under N-Heterocyclic Carbene Catalysis”, Org. Lett. 2022, 24, 7654.
5） Junxin Rao, Xiaoyu Ren, Xin Zhu, Zhen Guo*, Chengming Wang*, Cong-Ying Zhou*, “Ruthenium-catalyzed reaction of diazoquinones with arylamines to synthesize diarylamines”, Org. Chem. Front. 2022, 9, 5845.
6） Qijing Zhang, Hao Lei*, Cong-Ying Zhou*, Chengming Wang*, “Construction of N-Polyheterocycles by N Heterocyclic Carbene Catalysis via a Regioselective Intramolecular Radical Addition/Cyclization Cascade”, Org. Lett. 2022, 24, 4615.
7） Lixia Liu, Cong-Ying Zhou*, Chengming Wang*, “Construction of highly congested quaternary carbon centers by NHC catalysis through dearomatization”, Green Synth. Catal. 2022, doi.org/10.1016/j.gresc.2022.05.010.
8） Junxin Rao, Jianli Zhao, Xin Zhu, Zhen Guo,* Chengming Wang,* Cong-Ying Zhou*, “Rhodium-catalyzed reaction of diazoquinones with allylboronates to synthesize allylphenols”, Org. Chem. Front. 2022, 9, 3677.
9） Xuebo Gao, Rong Chang, Junxin Rao, Danyang Hao, Zhuxia Zhang, Cong-Ying Zhou,* Zhen Guo*, “Halogen-Bonding-Promoted C−H Malonylation of Indoles under Visible-Light Irradiation”, J. Org. Chem. 2022, 87, 8198.
10） Jin Bai, Sijia Yan, Zhuxia Zhang, Zhen Guo*, Cong-Ying Zhou*, “Visible Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions” Org. Lett., 2021, 23, 4843.
11） Bijin Lin, Xumu Zhang, Cong-Ying Zhou*, Chi-Ming Che*, “A PEGylated N-heterocyclic carbene-gold(I) complex: an efficient catalyst for cyclization reaction in water”, Org. Chem. Front., 2021, 8, 1216.
12） Sijia Yan, Junxin Rao, Cong-Ying Zhou*, “Chemoselective Rearrangement Reactions of Sulfur Ylide Derived from Diazoquinones and Allyl/Propargyl Sulfides” Org. Lett., 2020, 22, 9091.
13） Kai Wu, Liang-Liang Wu, Cong-Ying Zhou*, Chi-Ming Che*, “Transition‐Metal‐Free C(sp2)–C(sp2) Cross‐Coupling of Diazo Quinones with Catechol Boronic Esters” Angew. Chem. Int. Ed. 2020, 59, 16202.
14） Yi-Dan Du, Cong-Ying Zhou, Wai-Pong To, Hai-Xu Wang, Chi-Ming Che*, “Iron porphyrin catalysed light driven C–H bond amination and alkene aziridination with organic azides”, Chem. Sci., 2020, 11, 4680.
15） Hai-Xu Wang, Yann Richard, Qingyun Wan, Cong-Ying Zhou, Chi-Ming Che*, “Iridium(III)-Catalyzed Intermolecular C(sp3)-H Insertion Reaction of Quinoid Carbene: A Radical Mechanism”, Angew. Chem. Int. Ed. 2020, 59, 1845.
16）Kai Wu, Cong-Ying Zhou*, Chi-Ming Che*, “Perfluoroalkyl Aziridines with Ruthenium Porphyrin Carbene Intermediates”, Org. Lett. 2019, 21, 85.
17）Kai Wu, Bei Cao, Cong-Ying Zhou*, Chi-Ming Che*, “RhII-Catalyzed Intermolecular C-H Arylation of Aromatics with Diazo Quinones”, Chem.-Eur. J. 2018, 24, 4815.
18）Haixu Wang, Cong-Ying Zhou*, Chi-Ming Che*, “Cobalt-Porphyrin-Catalyzed Intramolecular Buchner Reaction and Arene Cyclopropanation of In Situ Generated Alkyl Diazomethanes”, Adv. Synth. Catal. 2017, 359, 2253.
19）Annapureddy Rajasekar Reddy, Fei Hao, Kai Wu, Cong-Ying Zhou*, Chi-Ming Che*, “Cobalt Porphyrin Catalyzed Intrmolecular Cyclopropanation of N-Alkyl Indoles/Pyrroles with Alkylcarbene: Efficient Synthesis of Polycyclic N-Heterocycles”，Angew. Chem. Int. Ed. 2016, 55, 1810.
20）Annapureddy Rajasekar Reddy†, Cong-Ying Zhou†, Zhen Guo, Jinhu Wei, Chi-Ming Che*, “Ruthenium Porphyrin Catalyzed Diastereoselective Intramolecular Alkylcarbene Insertion to C-H Bonds of Alkyldiazomethanes Generated In Situ from N-Tosylhydrazones”, Angew. Chem. Int. Ed. 2014, 53, 14175.
21）Annapureddy Rajasekar Reddy, Cong-Ying Zhou*, Chi-Ming Che*, “Ruthenium Porphyrin Catalyzed Three-Component Reaction of Diazo Compounds, Nitrosoarenes, and Alkynes: An Efficient Approach to Multifunctionalized Aziridines”, Org. Lett. 2014, 16, 1048.
22）Wenbo Xiao, Jinhu Wei, Cong-Ying Zhou*, Chi-Ming Che*, “[RuIV(F20-TPP)Cl2] efficiently catalysed inter- and intra-molecular nitrene insertion into sp3 C–H bonds of hydrocarbons using phosphoryl azides as nitrene sources” Chem. Commun. 2013, 49, 4619.
23）Jing Li, Justin S. Cisar, Cong-Ying Zhou, Brunilda Vera, Howard Williams, Abimael D. Rodríguez, Benjamin F. Cravatt, Daniel Romo*, “Simultaneous structure–activity studies and arming of natural products by C–H amination reveal cellular targets of eupalmerin acetate”, Nature Chemistry 2013, 5, 510.
24）Cong-Ying Zhou†, Jing-Cui Wang†, Jinhu Wei, Zhen-Jiang Xu, Zhen Guo, Kam-Hung Low, Chi-Ming Che*, “Dirhodium Carboxylates Catalysed Enantioselective Coupling Reactions of α-Diazophosphonates, Anilines and Electron Deficient Aldehydes”, Angew. Chem. Int. Ed. 2012, 51, 11376.
25）Annapureddy Rajasekar Reddy, Zhen Guo, Fung-Ming Siu, Chun-Nam Lok, Fuli Liu, Kai-Chung Yeung, Cong-Ying Zhou*, Chi-Ming Che*, “Diastereoselective Ruthenium Porphyrin-Catalyzed Tandem Nitrone Formation/1,3-Dipolar Cycloaddition for Isoxazolidines. Synthesis, in Silico Docking Study and in Vitro Biological Activities”，Org. Biomol. Chem. 2012, 10, 9165.
26）Wenbo Xiao, Cong-Ying Zhou, Chi-Ming Che*, “Ruthenium(IV) porphyrin catalyzed phosphoramidation of aldehyde with phosphoryl azide as nitrene source” Chem. Comm., 2012, 48, 5871.
27）Ming-Zhong Wang, Cong-Ying Zhou, Chi-Ming Che*, “A silver-promoted auto-tandem catalysis for the synthesis of multiply substituted tetrahydrocarbazoles” Chem. Comm., 2011, 47, 1312.
28）Cong-Ying Zhou, Jing Li, Satyamaheshwar Peddibhotla, Daniel Romo*, “Mild Arming and Derivatization of Natural Products via an In(OTf)3-Catalyzed Arene Iodination”, Org. Lett. 2010, 12, 2104.
29) Cong-Ying Zhou, Jie-Sheng Huang, Chi-Ming Che*, “Ruthenium Porphyrin-Catalyzed Carbenoid Transfer Reactions”, Synlett 2010, 2681.
30）Peng Liu, Cong-Ying Zhou, Song Xiang and Chi-Ming Che*, “Highly efficient oxidative carbon–carbon coupling with SBA-15-support iron terpyridine catalyst”, Chem. Comm., 2010, 46, 2739.
31）Chi-Ming Ho, Jun-Long Zhang, Cong-Ying Zhou, On-Yee Chan, Jessie Jing Yan, Fu-Yi Zhang, Jie-Sheng Huang, Chi-Ming Che*, “A Water-Soluble Ruthenium Glycosylated Porphyrin Catalyst for Carbenoid Transfer Reactions in Aqueous Media with Applications in Bioconjugation Reactions”, J. Am. Chem. Soc., 2010, 132, 1886.
32）Vanessa Kar-Yan Lo, Cong-Ying Zhou, Man-Kin Wong*, Chi-Ming Che*, “Silver(I)-mediated highly enantioselective synthesis of axially chiral allenes under thermal and microwave-assisted conditions”, Chem. Comm., 2010, 46, 213.
33）Cong-Ying Zhou, Chi-Ming Che*, “Highly Efficient Au(I)-Catalyzed Intramolecular Addition of β-Ketoamide to Unactivated Alkenes”, J. Am. Chem. Soc. 2007, 129, 5828.
34）Cong-Ying Zhou, Philip Wai Hong Chan, Chi-Ming Che*, “Gold(III) Porphyrin-Catalyzed Cycloisomerization of Allenones”, Org. Lett. 2006, 8, 325.
专著章节
[1] Chi-Ming Che, Vanessa Kar-Yan Lo, Cong-Ying Zhou, “Oxidation by Metals (Nitrene)”, Comprehensive Organic Synthesis II, 2014, V7, 26-85, Elsevier Ltd.
[2] Cong-Ying Zhou, Vanessa Kar-Yan Lo, Chi-Ming Che, “Metalloporphyrin-Catalyzed C-C Bond Formation”, Handbook of Porphyrin Science, World Scientific: Singapore, 2012, 21, 321-376.
[3] Chi-Ming Che, Cong-Ying Zhou, Ella Lai-Ming Wong, “Catalysis by Fe=X Complexes (X = NR, CR2)”, Topics in Organometallic Chemistry, 2011, 33, 111-138. Publisher: Springer GmbH.
承担课题
1） 国家自然科学基金面上项目 “金属卡宾参与的多组分反应和串联反应”(21472159)，主持人。
2）General Research Fund （香港研究资助局优配研究基金）“Transition metal catalyzed carbene transformations of non-stabilized diazoalkanes generated in situ from hydrazones”(17306714)，主持人。
3）广东省基础与应用基础研究基金项目“金属醌卡宾介导的叶立德转换反应”（2021A1515012023），主持人。
4）深圳市知识创新计划基础研究项目“过渡金属催化重氮化合物串联反应构建多取代杂环化合物”（JCYJ20150629151046879），主持人。
5）国家973项目 “金属配合物激发态的基础与应用研究”(2013CB834800)，科研骨干。
6）国家自然科学基金面上项目“过渡金属卟啉络合物催化的卡宾及氮宾碳氢键插入反应及其应用研究”（21272197），科研骨干。
讲授课程
有机化学，化学与材料概论，有机化学实验，生产实习
